November 11, 1994
Media Contact:Gary Stephenson
Phone: (410) 955-5384
E-mail: Gstephen@welchlink.welch.jhu.edu

Johns Hopkins has developed a research center dedicated to studies of the cause, prevention and treatment of heart attacks and strokes. The Johns Hopkins Thrombosis Center will place emphasis on blood clots and the role they play in heart disease.

"We want to determine, once and for all, how clots form to block arteries and veins that lead to the heart and brain," says Pascal Goldschmidt-Clermont, M.D., associate professor of cardiology and director of the Thrombosis Center.

Nearly 500,000 Americans die each year from problems related to the formation of blood clots. Five million new cases are diagnosed in the same time period, says Keaneth Baughman, M.D., director of the Hopkins division of cardiology. "Our strategy is to deploy several teams of specialists and get past the questions and answers only cardiologists have." The Center, in the Ross Research Building on the Hopkins medical campus, houses biomedical engineers, hematologists and neurologists as well as other doctors.

"Our aim is to raise new questions, find the answers and then provide state-of-the-art management to prevent and treat this type of heart disease," says Goldschmidt-Clermont.

Also at the center are experts in the immune response to thrombosis; the biophysics and biochemistry of clot formation; "shear" forces and clot formation; the biology of sticky and mobile molecules; normal and abnormal blood vessel growth, and the interaction between blood cells and vessel walls.

Funding will come from a private endowment.

The Thrombosis Center's work can already be seen in several abstracts accepted at this year's American Heart Association 67th Scientific Session. Please see press release titled: Refining the Treatment for Women with Unstable Angina.

-- JHMI --
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