March 16, 1994
Media Contact: Joann Rodgers
Phone: (410) 955-8659

Bert Vogelstein, M.D., a molecular biologist and Clayton Professor of Oncology with The Johns Hopkins Medical Institutions, has been chosen as this year's Passano Award Laureate for his studies on how gene mutations lead to the development and progression of cancer.

Vogelstein will deliver the 1994 Passano Foundation Lecture at the Hopkins School of Medicine at 4:30 p.m on April 18, in the Wood Basic Science Building Auditorium (725 North Wolfe St.). That night, Vogelstein is the guest of honor at a reception and dinner at the Maryland Club in Baltimore.

Since 1945, the Passano Foundation has been fulfilling its charter to scientific research and make an annual award recognizing outstanding research done in this country. Nineteen of the Passano award-winners have gone on to win a Nobel Prize.

This year's selection committee cited the Hopkins researcher for his work identifying genes involved in human hereditary colon cancer. Vogelstein's earlier studies, for example, resulted in identification of a major gene, called p53, whose mutations are common in colon, breast and other cancers. Recently, he and co-workers have isolated and explained the nature of another gene whose malfunction accounts for a sixth of all colon cancers.

The Passano Foundation's $100,000 annual awards program also supports the Clinician Scientist training program at the Hopkins School of Medicine by naming Passano Physician Scientists annually. For 1994, the recipients are Rajiv Ratan, M.D., Ph.D., and Jeffrey Balser, M.D., Ph.D.

-- JHMI --
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